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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Cy Young* | 7772.0 | 1890-1911 | |
| 2 | Joe Williams* | 7098.0 | 1907-1930 | |
| 3 | Walter Johnson* | 6582.0 | 1907-1927 | |
| 4 | Bill Foster* | 6090.0 | 1923-1949 | |
| 5 | Satchel Paige | 5938.0 | 1927-1951 | |
| 6 | Kid Nichols* | 5875.0 | 1890-1906 | |
| 7 | Ray Brown | 5527.0 | 1931-1953 | |
| 8 | Eddie Plank* | 5507.0 | 1901-1917 | |
| 9 | Grover Cleveland Alexander* | 5468.0 | 1911-1930 | |
| 10 | Luis Tiant Sr. | 5388.0 | 1926-1951 | |
| 11 | Eppa Rixey | 5263.0 | 1912-1933 | |
| 12 | Andy Cooper | 4972.0 | 1920-1942 | |
| 13 | Lefty Grove* | 4937.0 | 1925-1945 | |
| 14 | Henry McHenry# | 4905.0 | 1931-1954 | |
| 15 | Larry French | 4891.0 | 1929-1953 | |
| 16 | Charles Bender* | 4874.0 | 1903-1924 | |
| 17 | Paul Derringer | 4842.0 | 1931-1952 | |
| 18 | Leroy Matlock | 4823.0 | 1929-1952 | |
| 19 | Carl Hubbell* | 4693.0 | 1928-1948 | |
| 20 | Red Ames* | 4674.0 | 1903-1919 | |
| 21 | Hilton Smith | 4620.0 | 1932-1952 | |
| 22 | Christy Mathewson* | 4603.0 | 1900-1916 | |
| 23 | Eddie Cicotte* | 4601.0 | 1906-1923 | |
| 24 | Red Ruffing | 4597.0 | 1924-1946 | |
| 25 | Jose Mendez* | 4592.0 | 1907-1926 | |
| 26 | Dick Redding | 4561.0 | 1911-1931 | |
| 27 | Martin Dihigo | 4537.0 | 1924-1946 | |
| 28 | Jack Quinn | 4532.0 | 1909-1932 | |
| 29 | Jack Powell | 4504.0 | 1897-1912 | |
| 30 | Ed Brandt | 4435.0 | 1928-1950 | |
| 31 | Bill Holland | 4410.0 | 1919-1941 | |
| 32 | Rube Marquard | 4375.0 | 1908-1925 | |
| 33 | Ted Trent | 4317.0 | 1927-1949 | |
| 34 | Gus Weyhing | 4306.0 | 1887-1901 | |
| 35 | Babe Adams* | 4142.0 | 1906-1926 | |
| 36 | Vic Willis | 4131.0 | 1898-1910 | |
| 37 | Barney Brown | 4089.0 | 1931-1952 | |
| 38 | Roosevelt Davis | 4047.0 | 1924-1950 | |
| 39 | Van Mungo# | 4043.0 | 1931-1954 | |
| 40 | William Bell | 4015.0 | 1923-1942 | |
| 41 | Burleigh Grimes | 3988.0 | 1916-1934 | |
| 41 | Roy Partlow# | 3988.0 | 1934-1954 | |
| 43 | Leon Day# | 3977.0 | 1935-1954 | |
| 44 | Bill Doak | 3952.0 | 1913-1929 | |
| 45 | Red Faber | 3920.0 | 1914-1932 | |
| 46 | Bob Feller# | 3880.0 | 1936-1954 | |
| 47 | Bill Donovan | 3843.0 | 1898-1918 | |
| 48 | Bob Shawkey | 3841.0 | 1913-1927 | |
| 49 | Waite Hoyt | 3787.0 | 1919-1944 | |
| 50 | Amos Rusie | 3784.0 | 1889-1901 | |
| 51 | Dutch Leonard | 3756.0 | 1913-1925 | |
| 52 | Herb Pennock | 3723.0 | 1912-1934 | |
| 53 | Webster McDonald | 3719.0 | 1922-1940 | |
| 54 | Clark Griffith | 3716.0 | 1891-1911 | |
| 55 | Terris McDuffie | 3666.0 | 1930-1950 | |
| 56 | Rube Benton | 3622.0 | 1911-1925 | |
| 57 | Rube Waddell* | 3609.0 | 1897-1910 | |
| 58 | Schoolboy Rowe# | 3607.0 | 1933-1954 | |
| 59 | Tex Carleton | 3582.0 | 1932-1951 | |
| 60 | Mordecai Brown* | 3558.0 | 1903-1916 | |
| 61 | Dolf Luque | 3512.0 | 1914-1935 | |
| 62 | Lee Grissom | 3486.0 | 1934-1953 | |
| 63 | Ed Walsh* | 3482.0 | 1904-1914 | |
| 64 | Carl Mays | 3478.0 | 1915-1929 | |
| 65 | Harry Salmon | 3472.0 | 1920-1935 | |
| 66 | Porter Moss# | 3455.0 | 1932-1954 | |
| 67 | Bill Byrd | 3435.0 | 1932-1951 | |
| 68 | Al Orth | 3423.0 | 1895-1909 | |
| 69 | Dazzy Vance | 3409.0 | 1921-1935 | |
| 70 | Freddie Fitzsimmons | 3377.0 | 1925-1941 | |
| 71 | Phil Cockrell | 3372.0 | 1918-1934 | |
| 72 | Art Nehf | 3341.0 | 1915-1929 | |
| 73 | Hippo Vaughn | 3338.0 | 1909-1921 | |
| 74 | Doc White | 3321.0 | 1901-1912 | |
| 75 | Spud Chandler | 3314.0 | 1937-1952 | |
| 76 | Roy Welmaker | 3313.0 | 1933-1952 | |
| 77 | Sam Jones | 3308.0 | 1916-1935 | |
| 78 | Mel Harder# | 3307.0 | 1929-1954 | |
| 79 | Claude Passeau | 3287.0 | 1935-1954 | |
| 80 | Barney Morris | 3275.0 | 1932-1947 | |
| 81 | Slim Sallee | 3274.0 | 1908-1921 | |
| 82 | Jesse Haines | 3237.0 | 1919-1938 | |
| 83 | Fritz Ostermueller | 3223.0 | 1934-1952 | |
| 84 | Pink Hawley | 3195.0 | 1892-1901 | |
| 85 | Red Donahue | 3168.0 | 1893-1906 | |
| 86 | Joe McGinnity | 3162.0 | 1899-1908 | |
| 87 | Tommy Bridges | 3153.0 | 1930-1944 | |
| 88 | Dutch Leonard | 3149.0 | 1933-1954 | |
| 89 | Stan Coveleski | 3112.0 | 1915-1928 | |
| 90 | Brickyard Kennedy | 3108.0 | 1892-1903 | |
| 91 | Bill Dinneen | 3090.0 | 1898-1909 | |
| 92 | Bullet Rogan* | 3087.0 | 1915-1934 | |
| 93 | Lon Warneke | 3076.0 | 1930-1949 | |
| 94 | Addie Joss* | 3048.0 | 1902-1910 | |
| 95 | Claude Hendrix | 2983.0 | 1911-1920 | |
| 96 | Ted Breitenstein | 2982.0 | 1891-1901 | |
| 97 | Andy Porter# | 2951.0 | 1932-1954 | |
| 98 | Harry Howell | 2947.0 | 1898-1909 | |
| 99 | Earl Moore | 2900.0 | 1901-1913 | |
| 100 | Lefty Tyler | 2895.0 | 1910-1921 |
